Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair

To improve replication fidelity, mismatch repair (MMR) must detect non-Watson-Crick base pairs and direct their repair to the nascent DNA strand. Eukaryotic MMR in vitro requires pre-existing strand discontinuities for initiation; consequently, it has been postulated that MMR in vivo initiates at Ok...

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Autores principales: Ghodgaonkar, Medini Manohar, Lazzaro, Federico, Olivera-Pimentel, Maite, Artola-Borán, Mariela, Cejka, Petr, Reijns, Martin A., Jackson, Andrew P., Plevani, Paolo, Muzi-Falconi, Marco, Jiricny, Josef
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653069/
https://ncbi.nlm.nih.gov/pubmed/23603115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.019
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