Ribonucleotides Misincorporated into DNA Act as Strand-Discrimination Signals in Eukaryotic Mismatch Repair

To improve replication fidelity, mismatch repair (MMR) must detect non-Watson-Crick base pairs and direct their repair to the nascent DNA strand. Eukaryotic MMR in vitro requires pre-existing strand discontinuities for initiation; consequently, it has been postulated that MMR in vivo initiates at Ok...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ghodgaonkar, Medini Manohar, Lazzaro, Federico, Olivera-Pimentel, Maite, Artola-Borán, Mariela, Cejka, Petr, Reijns, Martin A., Jackson, Andrew P., Plevani, Paolo, Muzi-Falconi, Marco, Jiricny, Josef
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653069/
https://ncbi.nlm.nih.gov/pubmed/23603115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.03.019
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados