Expression of corticotropin releasing factor receptor type 1 (CRF(1)) in the human gastrointestinal tract and upregulation in the colonic mucosa in patients with ulcerative colitis

Brain corticotropin-releasing factor (CRF) acting on CRF receptor type 1 (CRF(1)) is a main signaling pathway in the stress response. CRF is also produced in a variety of peripheral sites and acts locally as a proinflammatory mediator. We investigated CRF(1) mRNA expression in the human gastrointest...

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Main Authors: Yuan, Pu-Qing, Wu, S.Vincent, Elliott, Julie, Anton, Peter A, Chatzaki, Ekaterini, Million, Mulugeta, Taché, Yvette
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652978/
https://ncbi.nlm.nih.gov/pubmed/22948128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2012.07.028
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