Conservation of promoter sequence but not complex intron splicing pattern in human and hamster genes for 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Regulation of the expression of 3-hydroxy-3-methyglutaryl coenzyme A (HMG-CoA) reductase is a critical step in controlling cholesterol synthesis. Previous studies in cultured Chinese hamster ovary cells have shown that HMG-CoA reductase is transcribed from a cholesterol-regulated promoter to yield a...
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| Published in: | Mol Cell Biol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
1987
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037337/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.1881-1893.1987 |
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