Sterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA.

A recombinant plasmid containing a full-length cDNA for hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase was introduced by calcium phosphate-mediated transfection into UT-2 cells, a mutant line of Chinese hamster ovary cells that lack 3-hydroxy-3-methylglutaryl coenzyme A reductase activity a...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Chin, D J, Gil, G, Faust, J R, Goldstein, J L, Brown, M S, Luskey, K L
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC366764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3838796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.5.4.634
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