The SOCS Box Domain of SOCS3: Structure and Interaction with the ElonginBC-Cullin5 Ubiquitin Ligase

Suppressor of cytokine signalling 3 (SOCS3) is responsible for regulating the cellular response to a variety of cytokines, including interleukin 6 and leukaemia inhibitory factor. Identification of the SOCS box domain led to the hypothesis that SOCS3 can associate with functional E3 ubiquitin ligase...

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Detalhes bibliográficos
Main Authors: Babon, Jeffrey J., Sabo, Jennifer K., Soetopo, Alfreda, Yao, Shenggen, Bailey, Michael F., Zhang, Jian-Guo, Nicola, Nicos A., Norton, Raymond S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652878/
https://ncbi.nlm.nih.gov/pubmed/18590740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.06.038
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