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Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection

Acute lung injury, sepsis, lung inflammation, and ventilator-induced lung injury are life-threatening conditions associated with lung vascular barrier dysfunction, which may lead to pulmonary edema. Increased levels of atrial natriuretic peptide (ANP) in lung circulation reported in these pathologie...

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Hlavní autoři: Birukova, Anna A., Zagranichnaya, Tatiana, Alekseeva, Elena, Bokoch, Gary M., Birukov, Konstantin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652875/
https://ncbi.nlm.nih.gov/pubmed/18064650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21354
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