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Parallel Solution Phase Synthesis of an Adenosine Antibiotic Analog Library

A library of eighty one adenosine antibiotic analogs was prepared under the Pilot Scale Library Program of the NIH Roadmap initiative from 5′-amino-5′-deoxy-2′,3′-O-isopropylidene-adenosine 3. Diverse aldehyde, sulfonyl chloride and carboxylic acid reactant sets were condensed to 3, in solution-phas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Moukha-chafiq, Omar, Reynolds, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652606/
https://ncbi.nlm.nih.gov/pubmed/23398694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/co300127z
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