PSGL-1/selectin and ICAM-1/CD18 interactions are involved in macrophage-induced drug resistance in myeloma

Chemoresistance is the major obstacle in multiple myeloma (MM) management. We previously showed that macrophages protect myeloma cells, on a cell contact basis, from melphalan or dexamethasone-induced apoptosis in vitro. In this study, we found that macrophage-mediated myeloma drug resistance was al...

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Main Authors: Zheng, Y., Yang, J., Qian, J., Qiu, P., Hanabuchi, S., Lu, Y., Wang, Z., Liu, Z., Li, H., He, J., Lin, P., Weber, D., Davis, RE., Kwak, L., Cai, Z., Yi, Q.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652581/
https://ncbi.nlm.nih.gov/pubmed/22996336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.272
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