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Cornichon proteins determine the subunit composition of synaptic AMPA receptors

Cornichon-2 and -3 (CNIH-2/-3) are AMPA receptor (AMPAR) binding proteins that promote receptor trafficking, and markedly slow AMPAR deactivation in heterologous cells, but their role in neurons is unclear. Using CNIH-2 and -3 conditional knock-out mice, we find a profound reduction of AMPAR synapti...

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Autors principals: Herring, Bruce E., Shi, Yun, Suh, Young Ho, Zheng, Chan-Ying, Blankenship, Sabine M., Roche, Katherine W., Nicoll, Roger A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652566/
https://ncbi.nlm.nih.gov/pubmed/23522044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.01.017
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