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Replication Fork Stability Is Essential for the Maintenance of Centromere Integrity in the Absence of Heterochromatin
The centromere of many eukaryotes contains highly repetitive sequences marked by methylation of histone H3K9 by Clr4(KMT1). This recruits multiple heterochromatin proteins including Swi6 and Chp1 to form a rigid centromere and ensure accurate chromosome segregation. In the absence of heterochromatin...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3652564/ https://ncbi.nlm.nih.gov/pubmed/23478021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.007 |
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