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Mutations Disrupting Histone Methylation Have Different Effects on Replication Timing in S. pombe Centromere

The fission yeast pericentromere comprises repetitive sequence elements packaged into heterchromatin marked by histone H3K9 methylation and Swi6 binding. Transient disruption of Swi6 during S phase allows a period of RNA synthesis which programs the RNAi machinery to maintain histone methylation. Ho...

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Detalhes bibliográficos
Main Authors: Li, Pao-Chen, Green, Marc D., Forsburg, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641051/
https://ncbi.nlm.nih.gov/pubmed/23658693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061464
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