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Mutations Disrupting Histone Methylation Have Different Effects on Replication Timing in S. pombe Centromere
The fission yeast pericentromere comprises repetitive sequence elements packaged into heterchromatin marked by histone H3K9 methylation and Swi6 binding. Transient disruption of Swi6 during S phase allows a period of RNA synthesis which programs the RNAi machinery to maintain histone methylation. Ho...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641051/ https://ncbi.nlm.nih.gov/pubmed/23658693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061464 |
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