Low molecular weight fibroblast growth factor-2 signals via protein kinase C and myofibrillar proteins to protect against postischemic cardiac dysfunction

Among its many biological roles, fibroblast growth factor-2 (FGF2) acutely protects the heart from dysfunction associated with ischemia/reperfusion (I/R) injury. Our laboratory has demonstrated that this is due to the activity of the low molecular weight (LMW) isoform of FGF2 and that FGF2-mediated...

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Detalhes bibliográficos
Main Authors: Manning, Janet R., Perkins, Sarah O., Sinclair, Elizabeth A., Gao, Xiaoqian, Zhang, Yu, Newman, Gilbert, Pyle, W. Glen, Schultz, Jo El J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652066/
https://ncbi.nlm.nih.gov/pubmed/23479264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00613.2012
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