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Synthesis of (13)C- and (14)C-labeled dinucleotide mRNA cap analogues for structural and biochemical studies

Herein we describe the first simple and short method for specific labeling of mono- and trimethylated dinucleotide mRNA cap analogues with (13)C and (14)C isotopes. The labels were introduced within the cap structures either at the N7 for monomethylguanosine cap or N7 and N2 position for trimethylgu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Piecyk, Karolina, Davis, Richard E., Jankowska-Anyszka, Marzena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652009/
https://ncbi.nlm.nih.gov/pubmed/22658555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2012.04.120
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