Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro.

In vitro mutagenesis of a 61-base-pair DNA sequence element that is necessary for induction of the c-fos proto-oncogene by growth factors revealed that a small region of dyad symmetry within the sequence element is critical for c-fos transcriptional activation. The same c-fos dyad symmetry element w...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Greenberg, M E, Siegfried, Z, Ziff, E B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365195/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3561415/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.3.1217-1225.1987
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