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Serum stimulation of the c-fos enhancer induces reversible changes in c-fos chromatin structure.

Transcription of the proto-oncogene c-fos is known to be activated by growth factors in serum and subsequently repressed by the Fos protein. We show that generalized DNase I sensitivity of c-fos chromatin correlates closely with enhancer activity during induction, repression, and superinduction of t...

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Autors principals: Feng, J L, Villeponteau, B
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC360979/
https://ncbi.nlm.nih.gov/pubmed/2106068
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