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Evidence for transcriptional and post-transcriptional control of the cellular thymidine kinase gene.

We have studied the cell cycle-regulated expression of the thymidine kinase (TK) gene in mammalian tissue culture cells. TK mRNA and enzyme levels are low in resting, G0-phase cells, but increase dramatically (10- to 20-fold) during the S phase in both serum-stimulated and simian virus 40-infected c...

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Bibliographic Details
Main Authors: Stewart, C J, Ito, M, Conrad, S E
Format: Artigo
Language:Inglês
Published: 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC365188/
https://ncbi.nlm.nih.gov/pubmed/3561412
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