Thymidine kinase synthesis is repressed in nonreplicating muscle cells by a translational mechanism that does not affect the polysomal distribution of thymidine kinase mRNA.

The molecular basis for replication-dependent expression of thymidine kinase (TK) activity (EC 2.7.1.21) was investigated in mouse skeletal muscle cells transformed with multiple copies of the chicken TK gene. When shifted to mitogen-depleted medium, proliferating myoblasts irreversibly withdraw fro...

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Bibliografische gegevens
Hoofdauteurs: Gross, M K, Merrill, G F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC297541/
https://ncbi.nlm.nih.gov/pubmed/2740335
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