Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter.

We characterized the activity of a human hsp70 gene promoter by in vitro transcription. Analysis of 5' deletion and substitution mutants in HeLa nuclear extracts showed that the basal activity of the promoter depends primarily on a CCAAT-box sequence located at -65. A protein factor, CCAAT-box-bindi...

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Bibliografische gegevens

Gepubliceerd in:	Mol Cell Biol
Hoofdauteurs:	Morgan, W D, Williams, G T, Morimoto, R I, Greene, J, Kingston, R E, Tjian, R
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Taylor & Francis 1987
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3561411/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.3.1129-1138.1987
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