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Two transcriptional activators, CCAAT-box-binding transcription factor and heat shock transcription factor, interact with a human hsp70 gene promoter.

We characterized the activity of a human hsp70 gene promoter by in vitro transcription. Analysis of 5' deletion and substitution mutants in HeLa nuclear extracts showed that the basal activity of the promoter depends primarily on a CCAAT-box sequence located at -65. A protein factor, CCAAT-box-...

詳細記述

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書誌詳細
主要な著者: Morgan, W D, Williams, G T, Morimoto, R I, Greene, J, Kingston, R E, Tjian, R
フォーマット: Artigo
言語:Inglês
出版事項: 1987
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC365185/
https://ncbi.nlm.nih.gov/pubmed/3561411
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