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Adora2b adenosine receptor signaling protects during acute kidney injury via inhibition of neutrophil-dependent TNF-α release()

Renal ischemia is among the leading causes of acute kidney injury (AKI). Previous studies have shown that extracellular adenosine is a prominent tissue-protective cue elicited during ischemia, including signaling events through the A2B adenosine receptor (Adora2b). To investigate the functional role...

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Detalhes bibliográficos
Main Authors: Grenz, Almut, Kim, Jae-Hwan, Bauerle, Jessica D., Tak, Eunyoung, Eltzschig, Holger K., Clambey, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651815/
https://ncbi.nlm.nih.gov/pubmed/23028059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201651
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