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Synstatin: a selective inhibitor of the syndecan-1-coupled IGF1R-αvβ3 integrin complex in tumorigenesis and angiogenesis
The syndecans are a family of heparan-sulfate-decorated cell surface proteoglycans, matrix receptors with roles in cell adhesion and growth factor signaling. Their heparan sulfate chains recognize “heparin-binding” motifs ubiquitously present in the extracellular matrix (ECM), providing the means fo...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651771/ https://ncbi.nlm.nih.gov/pubmed/23375101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12160 |
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