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Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila

Sir2 is the most intensively discussed longevity gene in current aging research. Although, the gene encoding for a NAD(+)-dependent histone deacetylase initially was found to extend lifespan of various organisms ranging from yeast to mammals, serious doubts regarding its role in longevity have been...

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Bibliografske podrobnosti
Main Authors: Hoffmann, Julia, Romey, Renja, Fink, Christine, Yong, Li, Roeder, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651523/
https://ncbi.nlm.nih.gov/pubmed/23765091
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