Characterization of pathogenic human monoclonal autoantibodies against GM-CSF

The origin of pathogenic autoantibodies remains unknown. Idiopathic pulmonary alveolar proteinosis is caused by autoantibodies against granulocyte–macrophage colony-stimulating factor (GM-CSF). We generated 19 monoclonal autoantibodies against GM-CSF from six patients with idiopathic pulmonary alveo...

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Detalhes bibliográficos
Main Authors: Wang, Yanni, Thomson, Christy A., Allan, Lenka L., Jackson, Linda M., Olson, Melanie, Hercus, Timothy R., Nero, Tracy L., Turner, Amanda, Parker, Michael W., Lopez, Angel L., Waddell, Thomas K., Anderson, Gary P., Hamilton, John A., Schrader, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651501/
https://ncbi.nlm.nih.gov/pubmed/23620516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216011110
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