Characterization of pathogenic human monoclonal autoantibodies against GM-CSF

The origin of pathogenic autoantibodies remains unknown. Idiopathic pulmonary alveolar proteinosis is caused by autoantibodies against granulocyte–macrophage colony-stimulating factor (GM-CSF). We generated 19 monoclonal autoantibodies against GM-CSF from six patients with idiopathic pulmonary alveo...

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Autori principali: Wang, Yanni, Thomson, Christy A., Allan, Lenka L., Jackson, Linda M., Olson, Melanie, Hercus, Timothy R., Nero, Tracy L., Turner, Amanda, Parker, Michael W., Lopez, Angel L., Waddell, Thomas K., Anderson, Gary P., Hamilton, John A., Schrader, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651501/
https://ncbi.nlm.nih.gov/pubmed/23620516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216011110
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