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Neutral forces acting on intragenomic variability shape the Escherichia coli regulatory network topology

Cis-regulatory networks (CRNs) play a central role in cellular decision making. Like every other biological system, CRNs undergo evolution, which shapes their properties by a combination of adaptive and nonadaptive evolutionary forces. Teasing apart these forces is an important step toward functiona...

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Detalles Bibliográficos
Main Authors: Ruths, Troy, Nakhleh, Luay
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651454/
https://ncbi.nlm.nih.gov/pubmed/23610404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217630110
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