Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses.

Cell lines were established which produced high titers (approximately 10(6) infectious units per ml) of amphotropic, replication-defective recombinant retroviruses which transduced sequences encoding either human purine nucleoside phosphorylase (PNP) or adenosine deaminase (ADA). These viruses also...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: McIvor, R S, Johnson, M J, Miller, A D, Pitts, S, Williams, S R, Valerio, D, Martin, D W, Verma, I M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3102947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.2.838
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