Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses.

Cell lines were established which produced high titers (approximately 10(6) infectious units per ml) of amphotropic, replication-defective recombinant retroviruses which transduced sequences encoding either human purine nucleoside phosphorylase (PNP) or adenosine deaminase (ADA). These viruses also...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: McIvor, R S, Johnson, M J, Miller, A D, Pitts, S, Williams, S R, Valerio, D, Martin, D W, Verma, I M
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1987
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365142/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3102947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.2.838
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