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Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II.

RNA polymerase II is inhibited by the mushroom toxin alpha-amanitin. A mouse BALB/c 3T3 cell line was selected for resistance to alpha-amanitin and characterized in detail. This cell line, designated A21, was heterozygous, possessing both amanitin-sensitive and -resistant forms of RNA polymerase II;...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Principais autores: Bartolomei, M S, Corden, J L
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365112/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3821724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.2.586-594.1987
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