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Localization of an alpha-amanitin resistance mutation in the gene encoding the largest subunit of mouse RNA polymerase II.

RNA polymerase II is inhibited by the mushroom toxin alpha-amanitin. A mouse BALB/c 3T3 cell line was selected for resistance to alpha-amanitin and characterized in detail. This cell line, designated A21, was heterozygous, possessing both amanitin-sensitive and -resistant forms of RNA polymerase II;...

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Bibliographic Details
Main Authors: Bartolomei, M S, Corden, J L
Format: Artigo
Language:Inglês
Published: 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC365112/
https://ncbi.nlm.nih.gov/pubmed/3821724
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