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Crystal Structure of Quinone Reductase 2 in Complex with Resveratrol,
Resveratrol has been shown to have chemopreventive, cardioprotective, and antiaging properties. Here, we report that resveratrol is a potent inhibitor of quinone reductase 2 (QR2) activity in vitro with a dissociation constant of 35 nM and show that it specifically binds to the deep active-site clef...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650734/ https://ncbi.nlm.nih.gov/pubmed/15350128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi049162o |
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