MEK inhibition increases lapatinib sensitivity via modulation of FOXM1

Lignende værker

• Pharmacologic Inhibition of mTOR Improves Lapatinib Sensitivity in HER2-Overexpressing Breast Cancer Cells with Primary Trastuzumab Resistance
  af: Gayle, Sylvia S., et al.
  Udgivet: (2012)
• Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling
  af: Peake, Bridgette F., et al.
  Udgivet: (2017)
• Correction: Growth differentiation factor 15 mediates epithelial mesenchymal transition and invasion of breast cancers through IGF-1R-FoxM1 signaling
  af: Peake, Bridgette F., et al.
  Udgivet: (2020)
• Insulin-Like Growth Factor-1 Receptor Signaling Increases the Invasive Potential of Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer Cells via Src-Focal Adhesion Kinase and Forkhead Box Protein M1
  af: Sanabria-Figueroa, Eduardo, et al.
  Udgivet: (2015)
• Mechanism of Lapatinib-Mediated Radiosensitization of Breast Cancer Cells is Primarily by Inhibition of the Raf>MEK>ERK Mitogen-Activated Protein Kinase Cascade and Radiosensitization of Lapatinib-Resistant Cells Restored by Direct Inhibition of MEK
  af: Sambade, Maria J., et al.
  Udgivet: (2009)