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A Mutant with Aberrant Extracellular LcrV-YscF Interactions Fails To Form Pores and Translocate Yop Effector Proteins but Retains the Ability To Trigger Yop Secretion in Response to Host Cell Contact

The plasmid-encoded type three secretion system (TTSS) of Yersinia spp. is responsible for the delivery of effector proteins into cells of the innate immune system, where these effectors disrupt the target cells' activity. Successful translocation of effectors into mammalian cells requires Yers...

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書目詳細資料
Main Authors: Harmon, Dana E., Murphy, Julia L., Davis, Alison J., Mecsas, Joan
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650545/
https://ncbi.nlm.nih.gov/pubmed/23475976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02011-12
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