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A Mutant with Aberrant Extracellular LcrV-YscF Interactions Fails To Form Pores and Translocate Yop Effector Proteins but Retains the Ability To Trigger Yop Secretion in Response to Host Cell Contact

The plasmid-encoded type three secretion system (TTSS) of Yersinia spp. is responsible for the delivery of effector proteins into cells of the innate immune system, where these effectors disrupt the target cells' activity. Successful translocation of effectors into mammalian cells requires Yers...

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Main Authors: Harmon, Dana E., Murphy, Julia L., Davis, Alison J., Mecsas, Joan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650545/
https://ncbi.nlm.nih.gov/pubmed/23475976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.02011-12
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