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Molecular Architecture of a Sodium Channel S6 Helix: RADIAL TUNING OF THE VOLTAGE-GATED SODIUM CHANNEL 1.7 ACTIVATION GATE
Voltage-gated sodium (Na(V)) channels are membrane proteins that consist of 24 transmembrane segments organized into four homologous domains and are essential for action potential generation and propagation. Although the S6 helices of Na(V) channels line the ion-conducting pore and participate in ch...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3650411/ https://ncbi.nlm.nih.gov/pubmed/23536180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462366 |
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