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A SILAC-based Approach Identifies Substrates of Caspase-dependent Cleavage upon TRAIL-induced Apoptosis

The extracellular ligand-induced extrinsic pathway of apoptosis is executed via caspase protease cascades that activate downstream effectors by means of site-directed proteolysis. Here we identify proteome changes upon the induction of apoptosis by the cytokine tumor necrosis factor–related apoptosi...

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Autori principali: Stoehr, Gabriele, Schaab, Christoph, Graumann, Johannes, Mann, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650350/
https://ncbi.nlm.nih.gov/pubmed/23319142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.024679
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