Analysis of Protein-Protein Interactions in Cross-talk Pathways Reveals CRKL Protein as a Novel Prognostic Marker in Hepatocellular Carcinoma

Deciphering the network of signaling pathways in cancer via protein-protein interactions (PPIs) at the cellular level is a promising approach but remains incomplete. We used an in situ proximity ligation assay to identify and quantify 67 endogenous PPIs among 21 interlinked pathways in two hepatocel...

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Detalhes bibliográficos
Main Authors: Liu, Chia-Hung, Chen, Tzu-Chi, Chau, Gar-Yang, Jan, Yi-Hua, Chen, Chun-Houh, Hsu, Chun-Nan, Lin, Kuan-Ting, Juang, Yue-Li, Lu, Pei-Jung, Cheng, Hui-Chuan, Chen, Ming-Huang, Chang, Chia-Fen, Ting, Yu-Shan, Kao, Cheng-Yan, Hsiao, Michael, Huang, Chi-Ying F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650343/
https://ncbi.nlm.nih.gov/pubmed/23397142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O112.020404
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