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Quantitative Liquid Chromatography-Mass Spectrometry-Multiple Reaction Monitoring (LC-MS-MRM) Analysis of Site-specific Glycoforms of Haptoglobin in Liver Disease

Development of liver disease is associated with the appearance of multiply fucosylated glycoforms of haptoglobin. To analyze the disease-related haptoglobin glycoforms in liver cirrhosis and hepatocellular carcinoma, we have optimized an LC-MS-multiple reaction monitoring (MRM) workflow for glycopep...

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Detalhes bibliográficos
Main Authors: Sanda, Miloslav, Pompach, Petr, Brnakova, Zuzana, Wu, Jing, Makambi, Kepher, Goldman, Radoslav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650340/
https://ncbi.nlm.nih.gov/pubmed/23389048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.023325
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