Platelet Proteome Analysis Reveals Integrin-dependent Aggregation Defects in Patients with Myelodysplastic Syndromes

Bleeding complications are a significant clinical problem in patients with myelodysplastic syndromes even at sufficient platelet counts (>50,000/μl). However, the underlying pathology of this hemorrhagic diathesis is still unknown. Here, we analyzed the platelet proteome of patients with myelodys...

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Hlavní autoři: Fröbel, Julia, Cadeddu, Ron-Patrick, Hartwig, Sonja, Bruns, Ingmar, Wilk, Christian M., Kündgen, Andrea, Fischer, Johannes C., Schroeder, Thomas, Steidl, Ulrich G., Germing, Ulrich, Lehr, Stefan, Haas, Rainer, Czibere, Akos
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2013
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650338/
https://ncbi.nlm.nih.gov/pubmed/23382103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.023168
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