Impaired cytotoxicity associated with defective natural killer cell differentiation in myelodysplastic syndromes

Natural killer cells are well known to mediate anti-leukemic responses in myeloid leukemia but their role in myelodysplastic syndromes is not well understood. Here, in a cohort of newly diagnosed patients (n=75), widespread structural and functional natural killer cell defects were identified. One s...

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Vydáno v:Haematologica
Hlavní autoři: Hejazi, Maryam, Manser, Angela R., Fröbel, Julia, Kündgen, Andrea, Zhao, Xiaoyi, Schönberg, Kathrin, Germing, Ulrich, Haas, Rainer, Gattermann, Norbert, Uhrberg, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4420213/
https://ncbi.nlm.nih.gov/pubmed/25682594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2014.118679
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