Biological Evaluation of pH-Responsive Polymer-Caged Nanobins for Breast Cancer Therapy

A series of doxorubicin-loaded polymer-caged nanobins (PCN(DXR)) were evaluated in vivo in a murine MDA-MB-231 xenograft model of triple-negative breast cancer. The cross-linked polymer cage in PCN(DXR) offers protection for the drug payload while serving as a pH-responsive trigger that enhances dru...

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Hlavní autoři: Lee, Sang-Min, Ahn, Richard W., Chen, Feng, Fought, Angela J., O'Halloran, Thomas V., Cryns, Vincent L., Nguyen, SonBinh T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650137/
https://ncbi.nlm.nih.gov/pubmed/20738118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn100560p
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