Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice

LXR (Liver X Receptors) act as “sensor” proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines. This study shows that deletion of LXR in mouse fed a high-cholestero...

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Detalhes bibliográficos
Main Authors: Pommier, Aurélien J. C., Dufour, Julie, Alves, Georges, Viennois, Emilie, De Boussac, Hugues, Trousson, Amalia, Volle, David H., Caira, Françoise, Val, Pierre, Arnaud, Philippe, Lobaccaro, Jean-Marc A., Baron, Silvère
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649972/
https://ncbi.nlm.nih.gov/pubmed/23675307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003483
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