Liver X Receptors Protect from Development of Prostatic Intra-Epithelial Neoplasia in Mice

LXR (Liver X Receptors) act as “sensor” proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence proliferation of different cell types including human prostatic carcinoma (PCa) cell lines. This study shows that deletion of LXR in mouse fed a high-cholestero...

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Autors principals: Pommier, Aurélien J. C., Dufour, Julie, Alves, Georges, Viennois, Emilie, De Boussac, Hugues, Trousson, Amalia, Volle, David H., Caira, Françoise, Val, Pierre, Arnaud, Philippe, Lobaccaro, Jean-Marc A., Baron, Silvère
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649972/
https://ncbi.nlm.nih.gov/pubmed/23675307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003483
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