Refinement of IKZF1 recombination hotspots in pediatric BCP-ALL patients

Chromosomal translocations resulting in chimeric fusion genes are prototypic for pediatric leukemia patients. The most known fusions are ETV6-RUNX1 or BCR-ABL1 in B-cell progenitor (BCP)-ALL, and rearrangements of MLL in pediatric ALL and AML. Genome-wide sequencing projects have revealed additional...

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Autors principals: Meyer, Claus, zur Stadt, Udo, Escherich, Gabriele, Hofmann, Julia, Binato, Renata, Barbosa, Thayana da Conceição, Emerenciano, Mariana, Pombo-de-Oliveira, Maria S, Horstmann, Martin, Marschalek, Rolf
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649816/
https://ncbi.nlm.nih.gov/pubmed/23675566
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