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COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in childhood B-cell precursor acute lymphoblastic leukemia. Because of its clinical importance, we previously mapped breakpoints of intragenic deletions and developed a multiplex PCR assay to detect recurrent intragenic ΔIKZF1. Since the m...

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Vydáno v:Oncotarget
Hlavní autoři: Lopes, Bruno Almeida, Meyer, Claus, Barbosa, Thayana Conceição, zur Stadt, Udo, Horstmann, Martin, Venn, Nicola C., Heatley, Susan, White, Deborah L., Sutton, Rosemary, Pombo-de-Oliveira, Maria S., Marschalek, Rolf, Emerenciano, Mariana
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5288169/
https://ncbi.nlm.nih.gov/pubmed/27419633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10590
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