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Exploring the Relationship between the Inhibition Selectivity and the Apoptosis of Roscovitine-Treated Cancer Cells

The antitumor activity of roscovitine was tested in four cervical carcinoma cells: C33A, HCE-1, HeLa, and SiHa. The effects of roscovitine on ATP Lite assay, cell cycle, and apoptosis were assessed. The Sub-G(1) DNA content occurred great increasing, and this indicates that apoptosis was induced qui...

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Detalhes bibliográficos
Main Authors: Cui, Chunying, Wang, Yaonan, Wang, Yuji, Zhao, Ming, Peng, Shiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3649549/
https://ncbi.nlm.nih.gov/pubmed/23691435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/389390
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