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Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells through Apoptosis-Inducing Effect

Alsterpaullone, a small molecule cyclin-dependent kinase (CDK) inhibitor, regulates the cell cycle progression. Beyond death-inducing properties, we identified the effect of alsterpaullone on cycle procedure and apoptosis of HeLa cell. It was found that alsterpaullone inhibited HeLa cells in a time-...

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Detalhes bibliográficos
Main Authors: Cui, Chunying, Wang, Yuji, Wang, Yaonan, Zhao, Ming, Peng, Shiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610382/
https://ncbi.nlm.nih.gov/pubmed/23577282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/602091
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