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Improved Analysis for Determining Diffusion Coefficients from Short Single-Molecule Trajectories with Photoblinking

Two Maximum Likelihood Estimation (MLE) methods were developed for optimizing the analysis of single-molecule trajectories that include phenomena such as experimental noise, photoblinking, photobleaching, and translation or rotation out of the collection plane. In particular, short, single-molecule...

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Main Authors: Shuang, Bo, Byers, Chad P., Kisley, Lydia, Wang, Lin-Yung, Zhao, Julia, Morimura, Hiroyuki, Link, Stephan, Landes, Christy F.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648847/
https://ncbi.nlm.nih.gov/pubmed/23215347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la304063j
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