Viral E3 ubiquitin ligase-mediated degradation of a cellular E3: viral mimicry of a cellular phosphorylation mark targets the RNF8 FHA domain

Viral hijacking of cellular processes relies on the ability to mimic the structure or function of cellular proteins. Many viruses encode ubiquitin ligases to facilitate infection, although the mechanisms by which they select their substrates are often unknown. The Herpes Simplex Virus type-1 encoded...

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Detalhes bibliográficos
Main Authors: Chaurushiya, Mira S., Lilley, Caroline E., Aslanian, Aaron, Meisenhelder, Jill, Scott, Daniel C., Landry, Sebastien, Ticau, Simina, Boutell, Chris, Yates, John R., Schulman, Brenda A., Hunter, Tony, Weitzman, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648639/
https://ncbi.nlm.nih.gov/pubmed/22405594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.02.004
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