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A Strongly Absorbing Class of Non-Natural Labels for Probing Protein Electrostatics and Solvation with FTIR and 2D IR Spectroscopies
A series of non-natural infrared probes is reported that consist of a metal-tricarbonyl modified with a -(CH(2))(n)- linker and cysteine-specific leaving group. They can be site-specifically attached to proteins using mutagenesis and similar protocols for EPR spin labels, which have the same leaving...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3648522/ https://ncbi.nlm.nih.gov/pubmed/23537223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp402946c |
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