Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator

BACKGROUND: Tumor-associated macrophages (TAM) promote malignant progression, yet the repertoire of oncogenic factors secreted by TAM has not been clearly defined. We sought to analyze which EGFR- and STAT3-activating factors are secreted by monocytes/macrophages exposed to tumor cell-secreted facto...

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Detalhes bibliográficos
Main Authors: Vlaicu, Philip, Mertins, Philipp, Mayr, Thomas, Widschwendter, Peter, Ataseven, Beyhan, Högel, Bernhard, Eiermann, Wolfgang, Knyazev, Pjotr, Ullrich, Axel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648435/
https://ncbi.nlm.nih.gov/pubmed/23597096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-197
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