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MicroRNA 9-3p Targets β(1) Integrin To Sensitize Claudin-Low Breast Cancer Cells to MEK Inhibition
MEK1/2 inhibitors such as AZD6244 are in clinical trials for the treatment of multiple cancers, including breast cancer. Targeted kinase inhibition can induce compensatory kinome changes, rendering single therapeutic agents ineffective. To identify target proteins to be used in a combinatorial appro...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3648081/ https://ncbi.nlm.nih.gov/pubmed/23530058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00269-13 |
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