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Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo.

Oncogenic activation of c-Myb in both avian and murine systems often involves N-terminal truncation. In particular, the first of three DNA-binding repeats in c-Myb has been largely deleted during the genesis of the v-myb oncogenes of avian myeloblastosis virus and E26 avian leukemia virus. This find...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Dini, P W, Lipsick, J S
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364804/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7334
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